"I definitely don't think that I'm hot doo-doo. I don't"

Drew Barrymore is expressing her lack of confidence in her own look. She is stating that she does not believe she is appealing or desirable. This could be translated as her being humble and not wanting to boast about her looks. It might likewise be translated as her being insecure and not feeling sufficient. It could be an indication of low self-confidence or a lack of self-love. Whatever the case may be, it is clear that Drew Barrymore does not believe highly of her own physical look. This might be due to a variety of aspects, such as societal pressures, personal insecurities, or perhaps her own self-criticism. Whatever the reason, it is clear that Drew Barrymore does not think she is "hot doo-doo".