"I don't agree with everything he did in his life, but we're dealing with this Howard Hughes, at this point. And also ultimately the flaw in Howard Hughes, the curse so to speak"

In this quote, Martin Scorsese is discussing his thoughts on Howard Hughes, a popular American business owner and filmmaker. He acknowledges that while he may not concur with everything Hughes performed in his life, he is specifically referring to the existing variation of Hughes that they are handling. This might recommend that Scorsese is concentrating on a particular time period or element of Hughes' life, rather than his entire life as a whole. Additionally, Scorsese discusses a "flaw" in Hughes, which he refers to as a "curse." This could suggest that there was something about Hughes that ultimately led to his failure or unfavorable repercussions in his life.