"I'll try anything once, twice if I like it, three times to make sure"

This quote by Mae West is a funny way of revealing her determination to try brand-new things. She is suggesting that she is open to trying something brand-new, but she will certainly not commit to it till she has actually attempted it several times. This could be taken her being cautious as well as not wishing to decide up until she is sure that it is the right one. It might likewise be interpreted as her being adventurous as well as wishing to see to it that she has actually experienced something fully prior to choosing. Regardless, it is a humorous way of expressing her willingness to try brand-new points as well as her wish to make certain that she is making the right decision.