"Little old ladies of both sexes. Why do I let them bother me?"

John O'Hara's quote is a reflection on the frustrations of handling senior people. He is questioning why he enables himself to be troubled by the "little old women of both sexes" he encounters. O'Hara is most likely referring to the elderly individuals he comes across in his life, such as in his neighborhood or at the store. He is most likely annoyed by their slow speed, their need for help, or their propensity to be forgetful. O'Hara's quote is a tip that we must be client and understanding with the senior, as they have lived a long life and deserve our regard. It is also a reminder that we ought to not enable ourselves to be irritated by the elderly, as they are often in need of our help and generosity. O'Hara's quote is a reminder that we ought to be patient and understanding with the elderly, and that we must not enable ourselves to be frustrated by them.