"Well, I don't know what Ron has in mind, but I do know about the arc of the show. Looking at how intuitive and instinctive Eddie and I play, that is the sort of thing that leads into sexual chemistry. I wouldn't be surprised if it emerged"

Mary McDonnell is referring to the possibility of an enchanting relationship between her personality as well as Eddie's personality in the show. She is recommending that the natural chemistry between the two characters can bring about a romantic connection. She is uncertain what the show's authors desire, yet she is open to the suggestion of an enchanting partnership in between both personalities. She believes that the all-natural chemistry in between both personalities could cause a charming connection, and she wouldn't be surprised if it occurred. This quote shows that McDonnell is open to the idea of a romantic relationship between the two personalities, and she is confident that the natural chemistry between them might bring about something much more. It is an exciting prospect for fans of the program, as well as it will be interesting to see if the writers determine to discover this possible partnership.