"You don't have to listen to those mean girls. They're just there to make you upset and make you feel bad about yourself. And you know, inside, they feel bad about themselves too. But they don't wanna admit it to anybody"

In this quote, Amanda Seyfried is motivating the reader to not let the unfavorable words and actions of others, specifically "mean women," affect them. She acknowledges that these individuals may try to bring others down in order to feel much better about themselves, however deep down, they also have problem with their own insecurities. Seyfried suggests that these people may not wish to confess their own feelings of inadequacy to anyone. In general, the quote serves as a tip to not let the upsetting words of others define one's self-respect and to have compassion for those who might be having problem with their own insecurities.