"My first appearance as a guest on The Tonight Show was in '81"

Garry Shandling's quote is a reflection on his profession and the impact that his very first look on The Tonight Show had on it. In 1981, Shandling made his first look as a guest on The Tonight Show, hosted by Johnny Carson. This look was a significant turning point in Shandling's profession, as it was his very first time appearing on a major late-night talk show. This appearance opened the door for Shandling to appear on other late-night programs, as well as to pursue his own projects, such as his effective comedy, The Larry Sanders Show. Shandling's quote is a suggestion of the importance of taking dangers and seizing chances, as his first appearance on The Tonight Show was a significant pivotal moment in his career. It is also a tip of the power of hard work and dedication, as Shandling had to put in the effort to make his very first appearance on The Tonight Show a success.