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Science Quote by Walter Gilbert

"Biology will relate every human gene to the genes of other animals and bacteria, to this great chain of being"

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Gilbert’s line has the clean inevitability of a lab result: once you can read genes at scale, the old boundaries between “us” and “everything else” collapse into shared code. The intent is partly promotional (genomics as the next organizing science) and partly philosophical, because it reframes identity as ancestry written in molecular language. Humans stop being a special case and become a data point in a continuous, testable family tree.

The subtext is a quiet provocation aimed at two audiences. To human exceptionalists, it says: you are not off the chain; you are inside it, stitched to bacteria as surely as to chimpanzees. To biologists, it promises a unifying method: if genes can be related across species, then function, disease, and evolution can be inferred, compared, predicted. “Relate” is doing heavy work here; it’s not just about similarity, but about mapping causes and constraints across deep time. A mutation in a fruit fly can illuminate a cancer pathway in a person because the pathway is older than both.

The context is the late-20th-century genomic turn, when sequencing was transforming from heroic one-offs into an industrial pipeline and the Human Genome Project was becoming a cultural object as much as a scientific one. Gilbert reaches back to “the great chain of being,” a pre-Darwin hierarchy, only to invert it: the chain isn’t a ladder of moral rank, it’s a network of kinship. The rhetorical punch is that modern biology doesn’t merely argue for connectedness; it itemizes it.

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Genes as Connections: Gilbert on the Great Chain of Being
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Walter Gilbert (born March 21, 1932) is a Scientist from USA.

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