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Science & Tech Quote by Sidney Altman

"Eight months later, having left Columbia, I was studying physics in a summer program and working in Colorado when I decided to enroll as a graduate student in biophysics"

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The drama here is almost aggressively un-dramatic: a life pivot delivered in the calm tone of a lab notebook. Altman compresses what would normally be a coming-of-age crisis into a clean timeline - “eight months later” - as if identity itself were a variable you can re-measure after a new set of experiments. That’s the point. The sentence performs a scientist’s faith that the self is something you can iteratively refine through work, not something you discover in a single epiphany.

The quiet bomb is “having left Columbia.” In mid-20th-century American prestige culture, leaving an elite track reads like failure or rebellion. Altman refuses that script. He doesn’t dramatize the rupture, he routes around it: physics summer program, job in Colorado, then the decision to enroll in biophysics. The subtext is competence through motion. He’s not pleading his case; he’s showing how quickly a supposedly derailed path can become a more accurate one.

Colorado matters too. It signals distance from institutional gravity - a literal widening of horizons - and aligns with a particular American myth of reinvention, minus the self-help sheen. The final turn toward biophysics lands as a hybrid choice: not a retreat from physics, but an expansion into life science at a moment when interdisciplinary work was becoming the new frontier. The intent isn’t to brag about flexibility; it’s to normalize it. Altman frames career as experimental design: you change conditions, collect data, and when the results are convincing, you commit.

Quote Details

TopicStudent
SourceSidney Altman — Autobiography, Nobel Prize in Chemistry 1989 (autobiographical note on NobelPrize.org describing his leaving Columbia, summer physics study, work in Colorado, and decision to enroll in biophysics).
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Sidney Altman's Transition to Biophysics
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About the Author

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Sidney Altman (May 7, 1939 - April 5, 2022) was a Scientist from Canada.

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