"Human affairs are so obscure and various that nothing can be clearly known"
About this Quote
The line works because of its calibrated extremity. “So obscure and various” is a double bind: not only is reality hard to see, it keeps changing shape. “Nothing can be clearly known” pushes past mild skepticism into rhetorical provocation, designed to humble the reader into intellectual modesty. It’s less epistemology-as-paralysis than epistemology-as-ethics: if you accept how partial your knowledge is, you become less eager to persecute, legislate, or wage war over alleged certainties.
Context matters. Erasmus writes in the pressure cooker of early modern Europe, when religious reform, new learning, and political power were colliding. Calls for purity and hard lines were intensifying; the stakes of being “right” could be imprisonment or death. His skepticism functions as a civic intervention: an argument for tolerance, patience, and reform through education rather than coercion.
Subtext: beware the people who speak most clearly about a world that isn’t. In Erasmus’s hands, doubt becomes a tool for peace.
Quote Details
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Citation Formats
APA Style (7th ed.)
Erasmus, Desiderius. (2026, January 17). Human affairs are so obscure and various that nothing can be clearly known. FixQuotes. https://fixquotes.com/quotes/human-affairs-are-so-obscure-and-various-that-47960/
Chicago Style
Erasmus, Desiderius. "Human affairs are so obscure and various that nothing can be clearly known." FixQuotes. January 17, 2026. https://fixquotes.com/quotes/human-affairs-are-so-obscure-and-various-that-47960/.
MLA Style (9th ed.)
"Human affairs are so obscure and various that nothing can be clearly known." FixQuotes, 17 Jan. 2026, https://fixquotes.com/quotes/human-affairs-are-so-obscure-and-various-that-47960/. Accessed 7 Feb. 2026.









