"Humor is by far the most significant activity of the human brain"
About this Quote
The intent is almost evangelical. By elevating humor above logic or memory, de Bono smuggles in an argument about intelligence that isn’t IQ-bound or credential-dependent. Humor rewards the nimble, not the dutiful. It’s a form of cognitive rebellion: you’re permitted to break rules, but only if you can land the new pattern cleanly. That makes laughter an audit of mental flexibility, a social signal that a group has successfully navigated ambiguity together.
The subtext carries a quiet critique of institutions that worship seriousness. If humor is “the most significant activity,” then workplaces, schools, and bureaucracies that treat jokes as distractions are misreading the brain’s core function. De Bono wrote in a postwar era that prized rational planning and managerial expertise; his insistence on humor pushes back against a culture that confuses solemnity with rigor. He’s telling you that the brain’s greatest trick isn’t computation. It’s re-perception: the ability to see differently, fast, and with pleasure.
Quote Details
| Topic | Witty One-Liners |
|---|---|
| Source | Unverified source: The Guardian: 'Iraq? They just need to think it through' (Edward de Bono, 2007)
Evidence: "Humour is by far the most significant activity of the human brain," he says.. This is a primary-source appearance (quoted directly from Edward de Bono) in a published interview/profile by Angela Balakrishnan. However, it is almost certainly not the *first* publication: Wikiquote attributes the s... Other candidates (1) Artifical Laughter - Positive Cognitive Science (Are Nakrem, 2011) compilation95.0% Are Nakrem. Humor is by far the most significant activity of the human brain. Edward De Bono Hobbes concludes that “t... |
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Citation Formats
APA Style (7th ed.)
Bono, Edward de. (2026, February 13). Humor is by far the most significant activity of the human brain. FixQuotes. https://fixquotes.com/quotes/humor-is-by-far-the-most-significant-activity-of-134293/
Chicago Style
Bono, Edward de. "Humor is by far the most significant activity of the human brain." FixQuotes. February 13, 2026. https://fixquotes.com/quotes/humor-is-by-far-the-most-significant-activity-of-134293/.
MLA Style (9th ed.)
"Humor is by far the most significant activity of the human brain." FixQuotes, 13 Feb. 2026, https://fixquotes.com/quotes/humor-is-by-far-the-most-significant-activity-of-134293/. Accessed 21 Feb. 2026.







