"Humour is by far the most significant activity of the human brain"
About this Quote
Humour works by forcing the mind to run two incompatible interpretations at once, then snapping them into a new alignment. That snap is not trivial. It’s a live demonstration of flexibility, of error-detection, of creative re-routing. You can feel de Bono’s agenda in the phrasing “by far”: he’s trying to shock us out of the prestige hierarchy that treats logic as serious and humour as frivolous. The subtext is clinical and political at the same time: rigid thinking is dangerous, and societies that can’t laugh (at themselves, at power, at dogma) tend to calcify.
Context matters. De Bono built a career selling tools for creativity to classrooms and boardrooms; humour becomes his most elegant proof-of-concept. A joke is lateral thinking you can’t ignore: it hijacks attention, rewards reframing, and spreads socially. Calling it the brain’s “most significant activity” is marketing, yes, but it’s also a rebuke to cultures that worship productivity while starving play. Humour, in this view, is cognition testing its own boundaries in public.
Quote Details
| Topic | Witty One-Liners |
|---|---|
| Source | Help us find the source |
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Citation Formats
APA Style (7th ed.)
Bono, Edward de. (2026, January 17). Humour is by far the most significant activity of the human brain. FixQuotes. https://fixquotes.com/quotes/humour-is-by-far-the-most-significant-activity-of-66987/
Chicago Style
Bono, Edward de. "Humour is by far the most significant activity of the human brain." FixQuotes. January 17, 2026. https://fixquotes.com/quotes/humour-is-by-far-the-most-significant-activity-of-66987/.
MLA Style (9th ed.)
"Humour is by far the most significant activity of the human brain." FixQuotes, 17 Jan. 2026, https://fixquotes.com/quotes/humour-is-by-far-the-most-significant-activity-of-66987/. Accessed 12 Feb. 2026.






