"I haven't given up on working... across the aisle on issues and maybe it'll take an election or two for that to fully ferment, maybe it you know sometimes it takes awhile for people to realize what the best path is"

This quote by David Axelrod suggests that it may take a while for individuals to come together and work throughout the aisle on problems. He believes that it might take an election or more for individuals to recognize what the best path is. This indicates that it may take some time for people to come to a contract on particular issues, and that it might take a couple of elections for individuals to recognize what the very best course is. Axelrod is recommending that it may take a while for individuals to come together and work together on issues, which it may take a couple of elections for individuals to recognize what the very best path is. He is enthusiastic that people will ultimately come together and collaborate on issues, but it might take some time for that to occur.