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Science Quote by George Wald

"I tell my students to try to know molecules, so well that when they have some question involving molecules, they can ask themselves, What would I do if I were that molecule?"

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Wald slips a mischievous human trick into the hard machinery of science: empathy. Not the sentimental kind, but a disciplined act of imagination that turns chemistry from a pile of facts into a cast of agents with motives, constraints, and habits. The line is a quiet rebuke to the way students are often trained to treat molecules as inert nouns to be memorized. Wald wants verbs: bind, twist, repel, seek stability, follow gradients. “What would I do if I were that molecule?” is a provocation that makes mechanism feel inevitable rather than arbitrary.

The intent is pedagogical, but the subtext is almost philosophical. He’s arguing that understanding in science isn’t just accumulation; it’s internalization so complete you can run the system in your head. It’s the difference between knowing that hemoglobin changes shape and being able to anticipate why a change in pH will nudge oxygen off the protein. Personification becomes a tool for prediction. By lending molecules a provisional “point of view,” students smuggle in the real drivers: energy minimization, entropy, geometry, environment.

Context matters: Wald was a biochemist who helped explain the chemistry of vision, a field where microscopic conformational shifts produce macroscopic experience. In that world, the molecule’s “choices” are the story. The quote also hints at a mid-century confidence that biology could be made legible through physical chemistry, but only if we taught people to think like the system itself. Wald’s wager is that the best scientists aren’t just good at answers; they’re fluent enough in the actors to generate the next question.

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TopicTeaching
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George Wald (November 18, 1906 - April 12, 1997) was a Scientist from USA.

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