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Science Quote by Manfred Eigen

"In theory, there is no difference between theory and practice. But, in practice, there is"

About this Quote

Eigen’s line is a scientist’s deadpan joke with a scalpel hidden inside it. It starts by granting the idealized fantasy of clean abstraction: in theory, the map and the territory match perfectly. Then the second sentence flips the table with the smallest possible twist of syntax. “But, in practice, there is” lands like a lab result that refuses to obey your elegant model. The humor works because it’s not ornamental; it’s diagnostic. It stages, in miniature, the experience of research itself: you can do everything “right” and still watch reality introduce friction, noise, and inconvenient edge cases.

The subtext is a warning against intellectual vanity. “Theory” here isn’t being mocked as useless; it’s being exposed as incomplete unless it survives contact with constraints: measurement error, messy systems, human factors, time, cost, and the sheer perversity of complex phenomena. Eigen, a Nobel-winning chemist known for thinking hard about self-organization and evolution at the molecular level, spent a career in domains where tiny deviations compound and where models are indispensable but never sovereign. That context matters: in such systems, practice doesn’t merely apply theory; it reveals what theory forgot to include.

The intent is also cultural: a quiet rebuke to people who treat ideas as finished products rather than working hypotheses. In an era that loves “evidence-based” slogans, Eigen reminds us that evidence is earned in the gap between what should happen and what stubbornly does. The punchline is that the gap is the point.

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TopicWitty One-Liners
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In theory, there is no difference between theory and practice. But, in practice, there is
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About the Author

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Manfred Eigen (May 9, 1927 - February 6, 2019) was a Scientist from Germany.

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