"Its not stress that kills us, it is our reaction to it"
About this Quote
Selye’s context matters. Mid-20th-century medicine was learning to describe how the body pays for chronic alarm: hormones, inflammation, wear-and-tear. His “general adaptation syndrome” framed stress as a physiological process, not merely a mood. So when he says reaction kills, he’s pointing to the long tail of sustained activation - the body stuck in “on.” The subtext is clinical: the same stimulus can be metabolized as challenge or as threat, and those pathways have different costs.
There’s also an ethical edge. The quote anticipates a culture that sells calm as a consumer choice and risks blaming individuals for systemic strain. Read carefully, it’s not a mandate to “relax” through sheer willpower; it’s a reminder that appraisal, coping, social support, sleep, and meaning-making are legitimate interventions. Selye’s intent is practical, almost engineering-minded: you may not control the load, but you can redesign the response so the organism survives.
Quote Details
| Topic | Stress |
|---|---|
| Source | Help us find the source |
| Cite | Cite this Quote |
Citation Formats
APA Style (7th ed.)
Selye, Hans. (n.d.). Its not stress that kills us, it is our reaction to it. FixQuotes. https://fixquotes.com/quotes/its-not-stress-that-kills-us-it-is-our-reaction-48550/
Chicago Style
Selye, Hans. "Its not stress that kills us, it is our reaction to it." FixQuotes. Accessed February 2, 2026. https://fixquotes.com/quotes/its-not-stress-that-kills-us-it-is-our-reaction-48550/.
MLA Style (9th ed.)
"Its not stress that kills us, it is our reaction to it." FixQuotes, https://fixquotes.com/quotes/its-not-stress-that-kills-us-it-is-our-reaction-48550/. Accessed 2 Feb. 2026.



