"Meanwhile, the originator of a theory may have a very lonely time, especially if his colleagues find his views of nature unfamiliar, and difficult to appreciate"
About this Quote
The phrasing is tactically modest. “May have” sounds restrained, almost polite, but it masks a sharper indictment of how science polices its borders. Novel ideas don’t just face evidentiary tests; they face aesthetic ones. Mitchell points to that with “unfamiliar” and “difficult to appreciate,” suggesting that colleagues aren’t only asking “Is it true?” but “Does it look like the kind of explanation we’re used to?” Appreciation becomes a gate: if a theory doesn’t fit the field’s mental furniture, it gets treated as bad taste.
Context matters: Mitchell championed the chemiosmotic theory of ATP synthesis, a framework initially resisted because it reframed bioenergetics around gradients and membranes rather than the more intuitive chemical intermediates many expected. His sentence reads like an after-action report from the trenches of paradigm shift: a reminder that innovation often arrives first as a social problem. The intent isn’t self-pity; it’s a warning label on originality.
Quote Details
| Topic | Loneliness |
|---|---|
| Source | Help us find the source |
| Cite |
Citation Formats
APA Style (7th ed.)
Mitchell, Peter D. (2026, January 16). Meanwhile, the originator of a theory may have a very lonely time, especially if his colleagues find his views of nature unfamiliar, and difficult to appreciate. FixQuotes. https://fixquotes.com/quotes/meanwhile-the-originator-of-a-theory-may-have-a-130577/
Chicago Style
Mitchell, Peter D. "Meanwhile, the originator of a theory may have a very lonely time, especially if his colleagues find his views of nature unfamiliar, and difficult to appreciate." FixQuotes. January 16, 2026. https://fixquotes.com/quotes/meanwhile-the-originator-of-a-theory-may-have-a-130577/.
MLA Style (9th ed.)
"Meanwhile, the originator of a theory may have a very lonely time, especially if his colleagues find his views of nature unfamiliar, and difficult to appreciate." FixQuotes, 16 Jan. 2026, https://fixquotes.com/quotes/meanwhile-the-originator-of-a-theory-may-have-a-130577/. Accessed 7 Feb. 2026.





