Skip to main content

Science Quote by Paracelsus

"Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy"

About this Quote

A physician-alchemist in plague-era Europe doesn’t offer comfort; he offers a calibration. Paracelsus’s line is a frontal assault on the medieval habit of sorting the world into pure cures and pure toxins, saints and sinners, safe and damned. He collapses that moral geography into a technical one: what matters isn’t the essence of a substance but the amount, the exposure, the conditions. The brilliance is how he smuggles a scientific worldview into a proverb. “Poison is in everything” reads like fatalism until the second clause flips it into agency: dosage is a human choice, a measurement, a discipline.

The subtext is professional and political. Paracelsus spent his career fighting scholastic medicine and its reverence for inherited authorities. This aphorism is a manifesto for empiricism: stop arguing from doctrine, start observing effects. It also justifies a then-radical practice - using potent, even frightening materials as treatments - while warning against the lazy romance of “natural” purity. Hemlock and honey, mercury and herbs: the body doesn’t care about your categories.

Context matters: this is the early modern pivot from symbolic medicine to something like pharmacology and toxicology. The sentence anticipates modern risk thinking: no zero-risk world exists, only managed tradeoffs. It’s why the quote still lands in debates about vaccines, alcohol, supplements, microplastics, and screen time - not because it’s “timeless,” but because it refuses absolutes. Paracelsus turns fear into a unit of measure, and morality into method.

Quote Details

TopicWisdom
SourceParacelsus (Theophrastus von Hohenheim), attributed phrase 'Sola dosis facit venenum' — English: 'All things are poison, and nothing is without poison; the dosage makes it either a poison or a remedy.' (see Wikiquote)
More Quotes by Paracelsus Add to List
Paracelsus on Poison and the Role of Dosage
Click to enlarge Portrait | Landscape

About the Author

Switzerland Flag

Paracelsus (November 11, 1493 - September 24, 1541) was a Scientist from Switzerland.

25 more quotes available

View Profile

Similar Quotes

Paracelsus, Scientist
John Fletcher, Dramatist