"Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy"
About this Quote
A physician-alchemist in plague-era Europe doesn’t offer comfort; he offers a calibration. Paracelsus’s line is a frontal assault on the medieval habit of sorting the world into pure cures and pure toxins, saints and sinners, safe and damned. He collapses that moral geography into a technical one: what matters isn’t the essence of a substance but the amount, the exposure, the conditions. The brilliance is how he smuggles a scientific worldview into a proverb. “Poison is in everything” reads like fatalism until the second clause flips it into agency: dosage is a human choice, a measurement, a discipline.
The subtext is professional and political. Paracelsus spent his career fighting scholastic medicine and its reverence for inherited authorities. This aphorism is a manifesto for empiricism: stop arguing from doctrine, start observing effects. It also justifies a then-radical practice - using potent, even frightening materials as treatments - while warning against the lazy romance of “natural” purity. Hemlock and honey, mercury and herbs: the body doesn’t care about your categories.
Context matters: this is the early modern pivot from symbolic medicine to something like pharmacology and toxicology. The sentence anticipates modern risk thinking: no zero-risk world exists, only managed tradeoffs. It’s why the quote still lands in debates about vaccines, alcohol, supplements, microplastics, and screen time - not because it’s “timeless,” but because it refuses absolutes. Paracelsus turns fear into a unit of measure, and morality into method.
The subtext is professional and political. Paracelsus spent his career fighting scholastic medicine and its reverence for inherited authorities. This aphorism is a manifesto for empiricism: stop arguing from doctrine, start observing effects. It also justifies a then-radical practice - using potent, even frightening materials as treatments - while warning against the lazy romance of “natural” purity. Hemlock and honey, mercury and herbs: the body doesn’t care about your categories.
Context matters: this is the early modern pivot from symbolic medicine to something like pharmacology and toxicology. The sentence anticipates modern risk thinking: no zero-risk world exists, only managed tradeoffs. It’s why the quote still lands in debates about vaccines, alcohol, supplements, microplastics, and screen time - not because it’s “timeless,” but because it refuses absolutes. Paracelsus turns fear into a unit of measure, and morality into method.
Quote Details
| Topic | Wisdom |
|---|---|
| Source | Paracelsus (Theophrastus von Hohenheim), attributed phrase 'Sola dosis facit venenum' — English: 'All things are poison, and nothing is without poison; the dosage makes it either a poison or a remedy.' (see Wikiquote) |
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