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Science Quote by Paracelsus

"Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy"

About this Quote

A physician-alchemist in plague-era Europe doesn’t offer comfort; he offers a calibration. Paracelsus’s line is a frontal assault on the medieval habit of sorting the world into pure cures and pure toxins, saints and sinners, safe and damned. He collapses that moral geography into a technical one: what matters isn’t the essence of a substance but the amount, the exposure, the conditions. The brilliance is how he smuggles a scientific worldview into a proverb. “Poison is in everything” reads like fatalism until the second clause flips it into agency: dosage is a human choice, a measurement, a discipline.

The subtext is professional and political. Paracelsus spent his career fighting scholastic medicine and its reverence for inherited authorities. This aphorism is a manifesto for empiricism: stop arguing from doctrine, start observing effects. It also justifies a then-radical practice - using potent, even frightening materials as treatments - while warning against the lazy romance of “natural” purity. Hemlock and honey, mercury and herbs: the body doesn’t care about your categories.

Context matters: this is the early modern pivot from symbolic medicine to something like pharmacology and toxicology. The sentence anticipates modern risk thinking: no zero-risk world exists, only managed tradeoffs. It’s why the quote still lands in debates about vaccines, alcohol, supplements, microplastics, and screen time - not because it’s “timeless,” but because it refuses absolutes. Paracelsus turns fear into a unit of measure, and morality into method.

Quote Details

TopicWisdom
Source
Later attribution: They Called Me Mad (John Monahan, 2010) modern compilationISBN: 9781101445877 · ID: N59vRqVTcm8C
Text match: 95.00%   Provider: Google Books
Evidence:
... Paracelsus ' insight was in realizing that it wasn't the poison as much as the size of the dose that was responsible . As he said , “ Poison is in everything , and no thing is without poison . The dosage makes it either a poison or a remedy ...
Other candidates (1)
Wenn ihr jedes Gift recht wollt auslegen, was ist, das nicht Gift ist? Alle Dinge sind Gift, und nichts ohne Gift, al...
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Citation Formats

APA Style (7th ed.)
Paracelsus. (2026, March 11). Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy. FixQuotes. https://fixquotes.com/quotes/poison-is-in-everything-and-no-thing-is-without-143408/

Chicago Style
Paracelsus. "Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy." FixQuotes. March 11, 2026. https://fixquotes.com/quotes/poison-is-in-everything-and-no-thing-is-without-143408/.

MLA Style (9th ed.)
"Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy." FixQuotes, 11 Mar. 2026, https://fixquotes.com/quotes/poison-is-in-everything-and-no-thing-is-without-143408/. Accessed 28 Mar. 2026.

More Quotes by Paracelsus Add to List
Paracelsus on Poison and the Role of Dosage
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About the Author

Paracelsus

Paracelsus (November 11, 1493 - September 24, 1541) was a Scientist from Switzerland.

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