"When it is not in our power to follow what is true, we ought to follow what is most probable"

This quote by Rene Descartes is a pointer that we must make every effort to make decisions based on realities and evidence, rather than relying on our own opinions or beliefs. It suggests that when we are not able to determine the truth, we should instead concentrate on what is probably to be true. This is a crucial tip that we should not be too fast to make choices without thinking about all the facts and evidence readily available. It also encourages us to be unbiased and think about various viewpoints when making decisions. Eventually, this quote motivates us to make decisions based upon what is more than likely to be real, instead of relying on our own viewpoints or beliefs.