"But the drugs are kind of like taboo, at least among me and my friends and the people I've worked with"

This quote by Ethan Suplee recommends that making use of drugs is not accepted amongst his social circle. He implies that drugs are seen as a taboo subject, and that his buddies and coworkers do not freely go over or condone their use. This could be due to a variety of reasons, such as a fear of judgement or a desire to maintain a specific image. It might likewise be because of an absence of understanding or understanding of the effects of drugs, or a basic hostility to the idea of using them. Whatever the reason, it is clear that drugs are not viewed as a favorable thing in the eyes of Ethan Suplee and his social circle.