"I cannot know anything of which there is and can be only one"

This quote by Leo Strauss is a reminder of the limits of human understanding. It suggests that there are certain facts that are beyond our understanding, which we can not know whatever. It suggests that there are some things that are so unique and singular that they can not be totally comprehended by the human mind. This could be describing the mysteries of deep space, or to the divine nature of God. It could likewise be interpreted as a warning against trying to understand the unknowable, and instead to accept that there are some things that are simply beyond our understanding. Eventually, this quote functions as a reminder that there are some things that we will never ever fully understand, which we need to be simple in the face of the unidentified.