"I can't tell you what that little ingredient is which makes that first person want to go on and aggressively do more, and the other person be content to not do that. It's a mystery, but it does happen"

Sam Donaldson's quote explores the enigmatic nature of human drive and ambition. The core of this statement depends on the observation of an essential distinction in human behavior and motivation-- why some individuals are moved to pursue goals with ruthless vigor, while others are content with a more tempered approach to life.

The "little active ingredient" Donaldson refers to is a metaphorical essence or trait that identifies those who aggressively seek more from those who are satisfied with their current state. This "ingredient" might incorporate a series of psychological, ecological, or perhaps hereditary aspects. It might include innate personality type, such as a high level of conscientiousness or intrinsic motivation, that make some individuals more inclined to take effort and push limits. Additionally, it might relate to external impacts such as training, life experiences, or socio-economic aspects that form one's aspirations and life trajectory.

Donaldson acknowledges the intricacy of this phenomenon by calling it a "mystery." This shows an understanding that human inspiration is not a one-size-fits-all principle. It varies from person to individual, affected by a special mix of aspects. Science and psychology have actually long studied drive and motivation, yet certain aspects stay elusive and difficult to quantify.

Moreover, this quote highlights a vital aspect of human diversity: the spectrum of aspiration and desire for achievement. Not everybody will aspire to the exact same goals or be driven by the exact same impulses, and that variety is naturally important. It's a recognition that different goals and inspirations add to the richness of human experiences and societal advancement.

In essence, Donaldson highlights the wonderfully unpredictable and varied tapestry of human desires, advising us to value the intricacies that make each person's journey and motivation noticeably their own.