"I think one of the major things a director has to do is to know his subject matter, the subject matter of his script, know the truth and the reality of it. That's very important"

Robert Wise's quote highlights the importance of a director's understanding of the subject of their script. He believes that a director must have a comprehensive understanding of the fact and reality of the script in order to successfully direct it. This suggests that a director should recognize with the characters, setting, plot, and themes of the script in order to properly portray them on screen. Understanding the subject matter of the script also enables the director to make creative decisions that will bring the script to life. By understanding the script, a director can ensure that the story is told in such a way that is both accurate and interesting. Eventually, Robert Wise's quote highlights the value of a director's knowledge of the script in order to develop a successful movie.