"Only the madman is absolutely sure"

This quote by Robert Anton Wilson suggests that certainty is a quality of the mentally unsteady. It implies that those who are sure of themselves and their beliefs are not in touch with reality. This could be interpreted as a caution against dogmatic thinking and a tip to remain open-minded. It could also be viewed as a pointer to question our own beliefs and to be familiar with our own predispositions. It could be analyzed as a call to be simple and to acknowledge that we do not understand everything. It might also be viewed as a tip to be knowledgeable about our own restrictions and to be open to gaining from others. Ultimately, this quote serves as a reminder to stay unbiased and to be aware of our own predispositions and constraints.