"People who are extremely inside their head, like he was, are caught in a neurosis that goes round and round. Then something will hook them and take them to their end and they can't control it"

This quote by Vincent D'Onofrio speaks to the concept of being "in one's head" and the repercussions of that. It recommends that when someone is too captured up in their own thoughts, they can become trapped in a cycle of neurosis. This neurosis can become so powerful that it can take control of the person and lead them to an end that they can not manage. This might be translated as a cautioning to be mindful of one's ideas and to be familiar with the power they can have more than one's life. It likewise speaks with the idea that often, no matter how hard we try, we can not manage the result of our lives. We should understand our ideas and bear in mind the power they can have more than us.