"Well, yeah, but I probably wasn't as open about my desperation"

Edie Falco's quote suggests that she was desperate for something, but she was closed about it. This could imply that she was dealing with something internally, but she was not willing to share it with anyone. She may have hesitated of being judged or humiliated, so she kept her sensations to herself. It might also mean that she was trying to stay favorable and not let her desperation program, so she kept it hidden. Whatever the case, it is clear that Edie Falco was handling something that she was not willing to show others. Her quote is a pointer that it is all right to be open about our battles and to look for aid when we need it.