"Well, you can't compete with a six foot five man in a wig"

This quote by Shemar Moore is most likely describing the truth that some individuals have advantages that others do not. In this case, the six foot 5 man in a wig has a physical benefit that the speaker does not. This could be analyzed as a metaphor for any situation in which somebody has a benefit that the speaker does not. It might be a physical benefit, such as height, or a mental benefit, such as intelligence. The quote is a reminder that it is not constantly possible to take on somebody who has a benefit that you do not. It is essential to recognize when somebody has an advantage and to accept that it may be challenging to take on them. Ultimately, the quote is a suggestion to be humble and to acknowledge that in some cases it is not possible to take on somebody who has an advantage.