"I saw a transvestite wearing a T-shirt that said 'Guess'"

This quote by Demetri Martin is an amusing observation of the irony of a transvestite using a T-shirt that reads "Guess". It implies that the drag queen is challenging the observer to think their gender identity. The quote is likewise a commentary on the fluidity of gender identity and the concept that gender is not always quickly recognizable. It suggests that gender is an intricate principle which it is not always possible to guess someone's gender identity based upon their look. The quote also highlights the significance of respecting people's gender identity and not making presumptions about somebody's gender based upon their look. It is a pointer that everybody should be treated with respect and that gender identity ought to be accepted and commemorated.