"I'm very picky and I'm in a situation where it's a big crossover"

Shia LaBeouf's quote recommends that he is very specific and selective about the projects he selects to work on. He is in a special scenario where he is able to work on jobs that cover numerous genres and interest a variety of audiences. This might indicate that he is able to work on projects that are both commercially effective and creatively meaningful. It might also mean that he has the ability to deal with tasks that are both mainstream and independent. By remaining in this situation, he has the ability to pick the projects he deals with, enabling him to be more selective and particular about the jobs he handles. This quote recommends that Shia LaBeouf is in a distinct position where he is able to work on projects that span several categories and appeal to a variety of audiences, enabling him to be more selective and picky about the jobs he handles.