"So, then you find yourself in a situation where you have to do things because they're on offer to you, because you don't have much self-respect left. You just can't say no, even to something that you've never done before. You just can't help yourself"

In this quote, Brian Molko is describing a sensation of being trapped and doing not have self-esteem. He suggests that sometimes we may find ourselves in a circumstance where we feel bound to do things that are presented to us, even if we don't necessarily want to or have actually never done them in the past. This could be due to a lack of self-regard, triggering us to feel like we have no option however to say yes. Molko also suggests that this absence of self-esteem can lead us to make impulsive choices and act against our better judgment. In general, the quote highlights the value of preserving dignity and being able to say no when essential.