"When the show's not around any more, it's going to be hard not to have her in my life"

In this quote, Gillian Anderson is revealing her sensations about a person who is no longer in her life. She mentions that when the program, most likely a TV show or project they dealt with together, is no longer around, it will be difficult for her to not have this person in her life. This suggests that the individual was a considerable part of her life and their lack will be deeply felt. It likewise suggests that their relationship was most likely formed through their work on the program and may not have actually existed outside of it. In general, the quote communicates a sense of loss and longing for somebody who was as soon as an important existence in Anderson's life.