"The most insignificant people are the most apt to sneer at others. They are safe from reprisals. And have no hope of rising in their own self esteem but by lowering their neighbors"

William Hazlitt, a renowned English author, masterfully encapsulates an extensive observation about human nature in this quote. At its core, Hazlitt's insight reviews the behavioral tendencies of those he refers to as "unimportant individuals"-- people who might feel insecure, helpless, or marginalized in their own lives. These sensations of insignificance might stem from a viewed inability to obtain personal growth or social recognition. As a result, such individuals turn to lessening others to feel a sense of superiority or elevation.

The phrase "most apt to sneer at others" suggests a reflexive urge to criticize, mock, or belittle those around them. By mentioning the perceived flaws or failures of others, they try to construct a veneer of supremacy or knowledge. This behavior can be understood as a defense mechanism, a misdirected effort to deal with one's own sensations of insufficiency or inability. Hazlitt suggests that such sneering is a purposeful option due to the fact that it brings little threat of retaliation or "reprisals". The sneerers view themselves as too insignificant to be genuine risks, therefore granting them a peculiar immunity in social characteristics.

Additionally, Hazlitt underscores the concept that these individuals lack "hope of rising in their own self-esteem but by reducing their next-door neighbors". This highlights an uncertainty or self-regard that can not be independently cultivated. Instead of looking for self-improvement, they discover short-term solace in the act of demeaning others. The lowering of others becomes a misguided methods of improving their self-view, albeit momentarily and unhealthily.

In general, Hazlitt's observation serves as both a critique of such habits and a challenge to readers to introspect about their own actions and mindsets. It prompts a reflection on whether one develops self-regard through authentic individual development or at the expense of others, encouraging a more understanding and useful approach to human interactions.